earticle

영어

The potential antioxidant activities of different fractions from a 70% methanolic (MeOH) extract of Sonchusoleraceus were assayed in vitro. All of the fractions exception of n-hexane showed a strong antioxidant activity, especially theethyl acetate (EtOAc) fraction, which showed the highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavengingactivity (IC50=19.25µg/mL). The results of hydroxyl radical scavenging activity and a reducing power assay showedconcentration dependence, the EtOAc fraction demonstrating a better result than the other fractions at the same concentrationin the studies. Additionally, the fractions’ total phenolic (TP) contents was measured, phenolic compounds such as tannic acid,p-coumatric acid, quercetin, epicathchin, and kaempferol being detected by high performance liquid chromatography (HPLC).Meanwhile, a regression analysis revealed a moderate-to-high correlation coefficient between the antiradical activity and theTP contents, suggesting that fractions obtained from the 70% MeOH extract of S. oleraceus are of potential use as sources ofantioxidant material.