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In vivo Antioxidative Characteristics of Extracts from the Aromatic Herb Elsholtzia splendens

원문정보

Eun Jeong Choi, Gun-Hee Kim

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초록

영어

The antioxidative properties of an Elsholtzia splendens ethanol extract (ESE) were examined in vivo. Oral administration of 10 or 50 mg ESE/kg BW in mice for 50 days resulted in a dose-dependent decrease in several biomarkers of oxidative stress including thiobarbituric acid reactive substance (TBARS), protein carbonyls, and serum 8-hydroxy-2'-deoxy guanosine (8-OH-dG). Moreover, the level of activity and mRNA expression of catalase and superoxide dismutase (SOD) were significantly increased by ESE treatment. Taken together, these results indicate that ESE may be beneficial to human health via its antioxidative properties.

목차

Abstract
 Introduction
 Materials and Methods
  Preparation of Elsholtzia splendens extract
  Animal care and serum analysis
  Determination of oxidative stress biomarkers
  Analysis of antioxidant enzymes
  Statistical analysis
 Results and Discussion
 References

저자정보

  • Eun Jeong Choi Plant Resources Research Institute, Duksung Women’s University
  • Gun-Hee Kim Plant Resources Research Institute, Duksung Women’s University

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자료제공 : 네이버학술정보

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