earticle

영어

This study aimed to assess the hair loss prevention effects of the dongeuihot spring water complex(Dongui Hot Spring Water CPX), which contains sea slug extract. The complex was created by dissolving sea slug extract and panthenol into dongeuihot spring water. The control group was prepared by dissolving the ingredients in distilled water instead of dongeui hot spring water. The results showed that as the concentration of Dongeui Hot Spring Water CPX increased, its DPPH radical scavenging activity significantly increased, demonstrating higher antioxidant activity compared to the control group made with distilled water. Similarly, the Dongeui Hot Spring Water CPX also showed a significant increase in ABTS radical scavenging activity as its concentration rose. Furthermore, when the toxicity of Dongeui Hot Spring Water CPX was tested on HFDPC cells, it was found to promote greater cell proliferation(cell viability) at all concentrations compared to the control group. Overall, Dongeui Hot Spring Water CPX exhibited higher cell proliferation than the control group. These results suggest that Dongeui Hot Spring Water CPX may help prevent hair loss by neutralizing free radicals around hair follicles. Additionally, Dongeui Hot Spring Water CPX was found to be non-toxic and did not inhibit the growth of hair papilla cells. The findings confirm that Dongui Hot Spring Water CPX contributes to the proliferation of hair papilla cells, helping prevent hair loss. Therefore, Dongui Hot Spring Water CPX can be considered a beneficial ingredient for improving scalp health and preventing hair loss.

중국어

本研究旨在验证含海蛞蝓提取物的东义温泉水复合物(东义温泉水CPX) 的防脱发效果. 东义温 泉水CPX由东义温泉水中溶解海蛞蝓提取物和泛醇制成, 对照组则使用蒸馏水代替东义温泉水 制成. 研究发现, 随着东义温泉水CPX浓度的增加, 其DPPH自由基清除能力显著增强, 且抗 氧化活性高于使用蒸馏水制成的对照组. 东义温泉水CPX在ABTS自由基清除能力方面也随着 浓度的增加而显著提高. 此外, 测量东义温泉水CPX对HFDPC细胞的毒性结果显示, 在所有 实验浓度下, 东义温泉水CPX比对照组具有更高的细胞增殖能力, 即东义温泉水CPX的细胞增 殖能力高于对照组. 从这些结果可以判断, 东义温泉水CPX能够清除毛囊周围的自由基, 因此 具有防脱发效果, 同时无抑制毛乳头细胞生长的毒性. 研究证实, 东义温泉水CPX通过促进毛 乳头细胞增