원문정보
Effect of Antioxidation and Inhibition of Melanogenesis from Scutellaria baicalensis Extract
초록
영어
Melanigenesis with basic cosmetic ingredients was investigated. skin lightening is one of the most important effect of functinal cosmetics, especially for the asian women. In this work, the extract of Scutellaria baicalensis and its key flavonoids such as baicalin, baicalein and wogonin were studied to characterize as a cosmetic ingredient. Anitoxidant activity of Scutellaria baicalensis extract was not very high but was high enough to be employed in cosmetics. When the Scutellaria baicalensis extract and the flavonoids were added to the culture media of B16F10 melanoma, the melanin production was inhibited concentration dependently and this effect was enough to be used as whitening material of cosmetics. Scutellaria baicalensis extract and the flavonoids were melaninmeasurement α-MSH inhibited concentration dependently. Baiclain, baicalein, wogonin 1 μM when compared with the control group there was significant.(p <0.01). The results of this flavonoid know that excellent whitening effect, and the next natural whitening ingredients that can be used in navigation could confirm that.
목차
Ⅰ. 서론
Ⅱ. 연구방법
1. 세포배양
2. 황금 열수 추출물 제조
3. 사용기기
4. 항산화 활성 측정
5. 멜라닌 생성 억제능 측정
Ⅲ. 연구결과 및 고찰
1. 황금 추출물의 HPLC 결과
2. 황금추출물의 항산화 효과
3. 황금 추출물의 멜라닌 생성 억제능
4.황금 주요 플라보노이드의 멜라닌 생성능
Ⅳ. 결론
참고문헌