원문정보
초록
영어
The present study describes the preliminary evaluation of the composition and beauty cosmetic biological activities of Viscum album L. extracts.
The 8 types of phenolic acids and flavonoids components in both hot water and ethanol extracts were identified. And, flavonoid components were identified 3 types in hot water , and 4 types in ethanol extract. The DPPH radical scavenging activities of hot water and ethanol extracts were measured as 62.55±0.035% and 72.0±0.024% respectively. Tyrosinase inhibitory activity of hot water and ethanol extracts were 63.94±0.0249% and 62.61±0.0124%, respectively. The Inhibition of NO(nitric oxide) production on the hot water and 95% ethanol extracts gradually increased with increasing concentration. In the case of V. album extracted by hot water, Hela, AGS and HT-29 cells showed very good growth in a 60㎍/㎖ solution, but cell growth was inhibited in a 100㎍/㎖ solution. In the case of V. album extracted by 95% ethanol, Hela cell growth gradually increased with increasing concentration. But AGS and HT-29 cell growth increased in 20㎍/㎖. On the other hand, cell growth tended to decrease in higher than 60㎍/㎖ concentrations. The microbial growths of S. aureus, E. coli, P. aeruginosa and S. typhimurium tested with hot water extract increased dependent on concentration. But growth of K. pneumoniae bacteria has increased until 300㎍/㎖, but antimicrobial activity started to appear at higher than 300㎍/㎖ concentrations. In these case of 95% ethanol extract, microbial growth of 5 strains growth depended on the concentration of the extract, and cell growth not inhibited in treated concentration(1,500㎍/㎖) of this study.
목차
1. Introduction
2. Material and Methods
2.1. Plant Material and Extraction
2.3. DPPH Free Radical Scavenging Activity
2.4. Tyrosinase Inhibitory Activity Assay
2.5. Statistical Analysis
3. Results and Discussion
3.1. DPPH Radical Scavenging Activity
3.2. Composition and Contents (mg%) of Phenolic Acids and Flavonoids
3.3. Tyrosinase Inhibition
3.4. Effects of Antitumor Activity
3.5. Inhibitory Effect of NO Production
3.6. Antimicrobial Activity
References