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Poster Session Ⅲ : 분류, 기능성, 이용 : PⅢ-04

Neuronal protective activity of Hericium erinaceum extracts

원문정보

Hyung-Jun Noh, Kang-Hyo Lee, Chang-Sung Jhune, Jae-Han Cho, Gi-Ho Sung, Kab-Yeul Jang, Sun-Young Um, Geum-Soog Kim, Seung-Eun Lee, Young-Ok Kim

한국버섯학회 버섯 제15권 1호 통권 23호 2011.05 pp.50-50
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

This study was carried out to investigate neuronal protective activity of fruiting body of Hericium erinaceum. In order to search the effective active compound against amyloid beta peptide-induced oxidative stress on neuronal cells, rat pheochromocytoma cells (PC12), Extracts of Hericium erinaceum were screened and evaluated using both the 2’,7’-dichlorofluorescin diacetate assay (DCF-DA), and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. According to above assays, Solvent partitions of extracts were selected for further purification and isolation of anti-Alzheimer’s disease compound as it exerted the highest protective effects against hydrogen peroxide (H2O2)-induced oxidative stress.

저자정보

  • Hyung-Jun Noh Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Kang-Hyo Lee Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Chang-Sung Jhune Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Jae-Han Cho Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Gi-Ho Sung Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Kab-Yeul Jang Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Sun-Young Um Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Geum-Soog Kim Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Seung-Eun Lee Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873
  • Young-Ok Kim Development of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumseong, Chungbuk, 369-873

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자료제공 : 네이버학술정보

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