원문정보
초록
영어
Chitosan is excellent biocompatible and biocompatible and is a plentiful material with a natural linear biopolyaminosaccharide and well established technological base. Chitosan is obtained by alkaline deacetylation of chitin, which is the principal component of protective cuticles of crustaceans such as crabs, shrimps, prawns, lobster etc. Due to its unique polymeric cationic character and its gel properties, chitosan has been examined extensively in the food industry, biomedical and pharmaceutical applications. Chitosan is usually used as a component in hydrogels for medical applications. In this study, we investigated the effect of pH of sodium polyphosphate (TPP) solution during the formation of chitosan hollow beads. The electrostatic attraction between the cationic amino groups of chitosan and the anionic groups of the TPP is the main interaction leading to the formation of chtosan hollow beads. The pH of TPP solution was an important factor acting the formation of clear hollow bubbles or loose mesh-like structure. The stable chitosan hollow beads formed through the complexation of chitosan with TPP may be a promising material for drug delivery.