원문정보
초록
영어
Effect of Sargassum confusum extract on the reduction of body weight gain and lipid contents in obese rats were evaluated to find natural materials with anti-obesity benefits. After inducing obesity by feeding 42.5% high-fat diet for 5 weeks, each 10 Sprague-Dawley rats were randomly assigned to high-fat diet control (HFD) group and high-fat diet group containing 3% Sargassum confusum extract (HFDSC). Weight gain of HFD group (2.96±0.31 g/day) was significantly (p<0.05) higher as compared to that of normal diet (ND) group (2.19±0.17 g/day). Weights of adipose tissues of HFD group were higher than those of ND group. Body weight gain of HFDSC group, however, was 2.36±0.24 g/day, which was significantly (p<0.05) lower by 21% than that of HFD group. In addition, weights of epididymal and perirenal adipose tissues were lower by 15% and 16%, respectively, as compared to those of HFD group. Biochemical analyses showed that concentration of triglyceride, total cholesterol, and fatty acids were significantly (p<0.05) lower in HFDSC group. These results suggest that Sargassum confusum extract has a high potential as an anti-obesity material by reducing weight gain and obesity-related factors in serum.
목차
서론
재료 및 방법
알쏭이모자반 추출물 제조
동물실험
식이조제
해부 및 장기적출
혈청 분석
통계처리 및 결과처리
결과 및 고찰
체중증가량 및 식이효율
간과 신장의 중량
지방조직의 중량
혈중 지질농도 측정
혈당 및 혈청 중 간기능 효소의 활성 측정
요약
문헌