원문정보
초록
영어
In this study, we investigated a dose-dependent hypolipidemic and antioxidant effects of tocotrienol-rich fraction (TRF) from grape seeds. After induction of hyperlipidemia for 4 weeks, rats were supplemented with different dose (5, 25, and 50 mg/kg BW/day) of TRF for 1 week. Oral administration of TRF (50 mg/kg BW/day) decreased the plasma triglyceride (TG, 162.6mg/dL), total cholesterol (TC, 83.7mg/dL), low density lipoprotein-cholesterol (LDL-C, 20.3mg/dL), malondialdehyde contents (MDA, 3.3 nmol/dL), and atherogenic index (AI, 2.0) compare to high-fat diet group. These data suggest that TRF supplementation has significant health benefits through the modulation of physiological functions that include various
atherogenic lipid profiles and antioxidative status in hyperlipidemia.
목차
Introduction
Materials and Methods
Results and Discussion
References