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영어

The beneficial effects derived from consuming natural antioxidants may not depend on the action of an individualantioxidant, but rather on the concerted action of several antioxidants naturally present. The aim of this study was to determinethe concentrations and combinations of antioxidants that can produce synergistic effects (SyEs). Quantification of the lipoperoxylradical scavenging capacity of antioxidants was carried out in a homogeneous model system where the free radicals wereproduced by the oxidation of methyl linoleate, initiated by the 2,2'-azobis (2,4-dimethylvaleronitrile). The greatest SyE (2.21,p<0.05) was seen in mixtures of all 4 antioxidants when used with concentrations of 15µM lycopene, 2.5µM vitamin E,0.16µM vitamin C, and 10µM β-carotene. Doubling the vitamin E concentration from 2.5 to 5.0µM in the mixture with all 4antioxidant reduced the SyE to 1.69 (p<0.05). Other combinations produced synergistic effects that ranged from 1.28 to 1.41.