earticle

영어

This study was performed to analyze various antioxidants, to evaluate the antioxidative activities, and to measurethe protective effect for gap junction intercellular communication (GJIC) to assess the functional potency of the cherry tomato.The ascorbic acid, lycopene, and β-carotene were measured at 503.4±9.6, 39.7±1.5, and 7.4±0.3mg/100g d.w., and α-, β+γ-,δ-tocopherol contents were measured at 8.3±0.1, 1.7±0.0, and 0.1±0.0mg/100g d.w., respectively. Cherry tomato extractusing hexane/acetone/EtOH (2:1:1, CTE) exhibited a ABTS radical scavenging activity with an IC50 value of 48.83±0.30µg/mL. The cherry tomato protected against the inhibition of GJIC induced by H2O2 in WB-F344 rat liver epithelial cells, and thereduction in phosphorylated Cx43 was most clearly correlated with the concentration of CTE. These results demonstrated thatthe cherry tomato harbors a wealth of potent antioxidants and might be protect human body against the inhibition of the GJICby toxic components.