earticle

영어

We extracted by three ways and we was identified ROS scavenging activity in Aderium (complex plant extract: Euryale ferox, Hericium erinaceum, and Adenosphora triphylla).1; 2; 3) There are shaking using 70% ethanol, SCF (super critical fluid system), and fermentation using Lactobacillus helveticus KCTC 3545 in three ways of extraction. Fermented extract was most highly among the three in ROS scavenging activity. We know that if effective material is fermented, it is increased nutritive component and it is reduced particle size of component, therefore it is evaluated penetration of skin. On the base of above results, we tried safety test in vivo and in vitro, efficacy test measuring such as moisturizing, TEWL (transepidermal water loss) in vivo. It was applied 1 % of extract on cream base and there was no cytotoxicity in cell assay using fibroblast and patch test. Moisturizing and TEWL value was shown a reciprocal curve and we observed increase and decrease between fermented Aderium (treatment) and
non-fermented Aderium (control) at 8 h. Treat part was superior 23 % of moisturizing value compare with control and TEWL value was lower than control (16 %). Hereby, we defined valuable activity in fermented Aderium. We will measure elasticity in vivo and will analyze main potential materials and then we will apply to commercial cosmetics product as new raw materials.