earticle

영어

The development of highly sensitive detection platforms is quite important to measure surface-generated signals due to the fact that biological signaling events as well as chemical adsorption behaviors generally occur on surfaces. Thus, a variety of surfaces fabrication methods have been applied to the sensitive and selective detection of biologically and environmentally relevant issues. Here, we present the effective monitoring methods via powerful surface analyzing techniques such as atomic force microscopy1-5) and surface plasmon resonance
spectroscopy,6-8) which allows real-time observation of phenomena on surfaces. The effective detections of environmental pollutants were successively achieved by the fabrication of miniaturized electrode systems9-11) and self-assembled smart sensing layers.12-16) In addition,
useful signals generated on surfaces were further amplified by some innovative methods, such as enlargement of surface area via mesoporous layer,17-18) multiplication of tiny signals via biomolecules19) and Au nanoparticles.20) The methods proposed here also provide the
feasibility of intelligent monitoring for the environmentally and biologically meaningful issues.