원문정보
초록
영어
The use of nanostructured materials in an intriguing approach for developing composite of enzyme-nanomaterials since these materials can provide a large surface area and new characteristics, which can lead to high volumetric enzyme activities and variety of different applications. Recent advances in enzyme aggregation via cross-linking are promising for the development of highly stable catalytic composite of bio-nanomaterials. Significant enhancement of enzyme stabilization was realized by forming cross-linked enzyme aggregates (CLEAs)
via cross-linker mediation coupled with various nanostructured materials such as nanofibers1),2),3), mesoporous silica4), or carbon nanotubes5). The stability of enzymes aggregated with nanomaterials was greatly enhanced with no measurable loss of activity over a month of observation under rigorous shaking conditions. The approach of enzyme aggregation with various nanostructured materials, yielding high activity and stability, creates a useful new biocatalytic immobilized enzyme systems with potential applications in biosensor,
bioremediation and bioconversion.