원문정보
초록
영어
A bacterial strain producing a high concentration of red pigment isolated from sediment that had been collected East China Sea, Which was recorded as JE-34. It was identified as Zooshikella sp. JE-34 as based on the 16S rRNA gene sequence. The strain was produced pigment that showed characteristics similar to prodigiosin, as it is insoluble in water and has a red colour with a metallic green sheen. Prodigiosin has been reported a maximum absorption of 535-540
nm [1]. To date, prodigiosin and its analogues which have been shown to haveanticancer, cytotoxic and immunosuppressive activities have been isolated from Serratia marcescens, and chemically synthesized [2].
The radical scavenging activities of the extracts from JE-34 cell (ZC) and culture broth (ZB) according to extraction solvents and fractions on hydroxyl, alkyl and DPPH radical were investigated using a ESR spectrometer and compared with the ESR signal intensity.
Electron donating abilities (EDAs) of ZC acetone extract (ZCAE) and ZC ether soluble fraction (ZCfr.E) were 95.74% and 94.51% at 0.5㎎/㎖ respectively. The hydroxyl radical scavenging ability of the ZC hot water extract (ZC70E) was highest (59.08% at 1㎎/㎖), and alkyl radical scavenging ability was highest in the ZC water extract (ZC25E; 84.05% at 1㎎/㎖). From these results, ZC extracts and fractions had strong antioxidant activities.