earticle

영어

Anthriscus sylvestris is a perennial herb which belongs to the Umbelliferae family and its dried root has been used as a herbal medicine in Korea, Chian. The roots are used in therapy for digestion promotion, nutrition strengthening, the pollakiuria of old age, the discharge of phlegm, the removal of fever, and toothache. This experiment was conducted to investigate cytotoxicity of the ethanol extracts of stem, leaves, root, and whole plant from Anthriscus sylvestris against a human gastric carcinoma cell (SNU-601 cell line) and a human pulmonary carcinoma cell (Calu-6 cell line). The results showed that the cytotoxicity of these extracts were leaves, stem, whole plant, and root against two cell lines in sequence. In particular, leaves extract at the concentration of 800 ㎍/㎖ was inhibited above ninety percent on the growth of two cancer cell lines and at the concentration of 400 ㎍/㎖ was inhibited about fiftytwo percent and seventyseven percent against SNU-601, Calu-6 cell growth, respectively. Stem extract at 800 ㎍/㎖ was also inhibited above fifty percent against two cancer cell lines. This result represents that Anthriscus sylvestris would be a potential antitumor resource.