원문정보
초록
영어
Lindera erythrocarpa is distributed widely throughout Hanla mountain of Jeju and East Asia. In order to evaluate the utilizing possibility as antioxidant activity and melanin synthesis inhibite effect were investigated using ethanol extract and its fractions from L. erythrocarpa leaf. The EtOAc fractions showed the strongest antioxidant activites; DPPH IC50 7.43 ug/ml, Uric acid generation activity IC50 5.56 ug/ml, Superoxide generation activity IC50 16.86ug/ml, respectively. Phytochemical investigations led to the isolation of nine compound : quercetin(1), quercitrin(2), caffeic acid ethyl ester(3), cinamic acid methyl ester(4), methyl linderone(5), kanakugiol(6), kaempferol-3-Orhamnopyranoside(7), quercetin-3 -O-arabinofuranoside(8) and lucidone(9), as characterized by spectroscopic techniques including 1D, 2D NMR and HR-MS. Lucidone in nine compound was acting as a potent tyrosinase inhibitor(IC5010ug/ml) and melanin content inhibite(IC50 8ug/ml) compared to controls (arbutin). We suggesting that the leaf extract of this plant could be used as a source of natural antioxidants useful as potential cosmetic ingredient additives.