원문정보
초록
영어
Mungbean(Phaseolus radiatus) has been used for the relief of heat and blood pressure & cholesterol, promotion of urination, treatment of pesticide and lead poisoning and treatment of burn. Especially, it is known to have distinguished strong activity for various skin diseases. GABA is known as a neurotransmitter. It was recently reported that topical application of GABA accelerated barrier recovery on damaged skin and played an important part on skin barrier homeostasis. In this study, mungbean extract was fermented by Lactobacillus sakei B2-16 a GABA producing Lactobacillus strain. The resulting fermentation product contained up to 4 % GABA, organic acids such as lactic acid and mungbean peptides naturally hydrolyzed by a unique fermentation process. Antiinflammation efficacy of the fermented mungbean was analyzed by in vitro and in vivo using animal model and found that it had a strong anti-inflammatory activity. In addition. it markedly enhanced the collagen synthesis in cultured fibroblasts. Results showed that the mungbean fermentation extract could be used for cosmetics as a skin soothing active ingredient.