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The Effect of Structural Modification with Acetylation on Immune Activity

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In this study, the correlation between structural characterization and immuno-stimulating activity was investigated. This work was based on the structural characterization affecting molecular immuno-modulating activity of polysaccharide. The correlation was established through onverting the structure of polysaccharide by acetylation and determining NO production indicating the immune activity. The degree of acetylation of polysaccharide was measured by FT-IR, In results, it was found that NO production was increased with the increase of acetylation, resulting in showing the high immune activity.

저자정보

  • Jae Wan Wee Department of Bioengineering and Technology, Kangwon National University
  • Hee Hwan Lee Department of Bioengineering and Technology, Kangwon National University
  • Eock Kee Hong Department of Bioengineering and Technology, Kangwon National University

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