원문정보
초록
영어
A halophyte Salicornia herbacea (known as glasswort) was collected from Daebudo, Ansan in Korea. Active compound from Salicornia herbacea was isolated using HPLC technique. The structure of this compound was determined by extensive 2D-NMR analyses. The free radical scavenging activities of the compound on 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl radical (.OH) and carbon-centered radical were investigated using electron spin resonance (ESR) spectroscopy. Increased concentration of the compound exhibited a dose dependent scavenging activities on generation of DPPH, hydroxyl and carbon-centered radicals. It not only scavenged 30, 69, 78 and 85% on generation of DPPH radical at 3.125, 6.25, 12.5, and 25 μg/ml, respectively, but also scavenged 66, 77, 86 and 92% on hydroxyl radical at 3.125, 6.25, 12.5, and 25 μg/ml, respectively. In addition, it showed more than 85% scavenging effect on carbon-centered radical at the various concentrations. Therefore, these results suggested that this active compound from Salicornia herbacea could be developed as a candidate for potential natural antioxidant.