earticle

논문검색

inhibitory effects of a herb remedy extracts on nitric oxide synthesis in RAW 264.7 macrophage cells

초록

영어

the purpose of this study was to assess the effects of a herb remedy . on the cell proliferation, inducible nitric oxide synthase (inos) mRNA gene expression and nitric oxide (NO) production in RAW 264.7 macrophage cells. For the screening of anti-inflammation, a ethanolic extract of traditional herbal medicine was examined its inhibitory effect, and we confirmed that 1 herb.
NO concentrations were determined by measuring the amount of nitrite in the LPS treated-macrophage cell culture supernatant using Griess reagent. In cytotoxicity test, with the a herbal remedy concentration of up to 500 mg/mL, no significant effect on RAW 264.7 macrophage cells morphology and viability was observed compared to the control during the culture period.
Also, more than the concentration of 125ppm, a herbal remedy was significantly decreased the production of NO. As a result, we knew inhibitory effects of a herbal remedy extracts on Nitric Oxide synthesis in RAW 264.7 macrophage cells.

저자정보

  • Hye-Sung Youm department of biological engineering, Incheon
  • Tae- Ryeon Heo department of biological engineering, Incheon

참고문헌

자료제공 : 네이버학술정보

    함께 이용한 논문

      ※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.

      0개의 논문이 장바구니에 담겼습니다.