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논문검색

In silico improvement and application of organisms using the metabolite availability

원문정보

Tae Yong Kim, Hyun Uk Kim, Sang Yup Lee

한국생물공학회 한국생물공학회 학술대회 2008 춘계학술대회 및 국제심포지움 2008.04 pp.269-269
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

This study presents an in silico method for improving an organism on the basis of the flux sum (Φ), metabolite availability, and more particularly to a method for screening key metabolites that increase production yield of a useful substance. The method shows the metabolite utilization of an organism for producing a useful substance as flux sum and perturbing the flux sum, as well as a method for improving an organism producing a useful substance.
[This work was supported by the Korean Systems Biology Project of the Ministry of Science and Technology (M10309020000-03B5002-00000). Further supports by the LG Chem Chair Professorship and KOSEF through the CUPS are appreciated].

저자정보

  • Tae Yong Kim Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering(BK21program), Korea Advanced Institute of Science and Technology
  • Hyun Uk Kim Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering(BK21program), Korea Advanced Institute of Science and Technology
  • Sang Yup Lee Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering(BK21program), Korea Advanced Institute of Science and Technology, Department of BioSystems, BioProcess Engineering Research Center and Bioinformatics Research Center, Korea Advanced Institute of Science and Technology,

참고문헌

자료제공 : 네이버학술정보

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