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Formation of micro-plug in microfluidic device using water immiscible room temperature ionic liquids

초록

영어

A microfluidic device is a miniaturized analytical system in which pretreatment, reaction, separation, detection and analysis are integrated. The advantages are consumption of a small volume of reagent, short time for analysis, higher accuracy, easier automation and scale-up, etc. Room temperature ionic liquids (RTILs) are organic salts which do not crystallize at room temperature. RTILs are gaining increasing notoriety and investigation as green solvents, because of thier non-volatile character, thermal stability, versatility, and so forth. Formation a micro-plug of RTILs in a microfluidic device is useful for high-throughput application, such as chemical processing, DNA analysis, polymerization, etc. In this study, size-distribution of RTIL micro-plug in PDMS (polydimethyl siloxane)-based microfluidic device was investigated.1) The effect
of flow rates of PBS (phosphate buffered saline) and RTILs on the size of micro-plug was determined. The interfacial tension proportionally increased in relation on the length of the alkyl chain of the RTILs. Consequently, capillary number was calculated for the estimation of the size of the micro-plug.2)

저자정보

  • Joo-Hyung Choi Department of Biological Engineering
  • Sang-Hyun Lee ERC for Advanced Bioseparation Technology, Inha University
  • Sung-Ho Ha ERC for Advanced Bioseparation Technology, Inha University
  • Woo-Jin Chang ERC for Advanced Bioseparation Technology, Inha University
  • Yoon-Mo Koo Department of Biological Engineering, ERC for Advanced Bioseparation Technology, Inha University

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