원문정보
초록
영어
Protein adsorption on single-walled nanotube field effect transistors (FETs) leads to appreciable changes in the electrical conductance of the devices, a phenomenon that can be exploited for label free detection of biomolecules with a high potential for miniaturization. This work presents an elucidation of the electronic biosensing in immune reaction with a newly developed
microarray of nanotube "micromat" sensors. First, anti-human IgG was immobilized by 1-pyrenebutanoic acid succinimidyl ester on carbon nanotube surface1). And then, the introduction of human IgG at various concentrations caused a decrease in the source-drain current. Thus, because the CNT-FET biosensor can detect immune reaction, it is able to use for various disease diagnosis.