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Control of Bacterial Adhesion or Detachment by Electrical Energy

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Bacterial adhesion is an initial stage of biofilm formation. As biofilm has strong resistance to the conventional disinfectants and antimicrobials, control of bacterial adhesion is important to prevent biofilm formation. Bacteria have various surface groups such as flagella, flimbriae, lipopolysaccharides and so on. When bacteria adhere on surfaces, these surface groups bind specifically. Three major forces, van der Waals force, electrostatic force, and acid base interaction, are known to be related to adhered bacteria on solid surfaces. Bacterial adhesion can be controlled by changing hydrophobicity, surface free energy, and roughness of solid surfaces. Applying electrical energy on the surface can be one of the most effective ways since it is not only applicable extensively to any conductive surfaces but also environmental-friendly. This talk will cover the overview of bacterial adhesion or detachment studies by diverse electrical methods. This technology has been studied for antifouling of marine underwater structures ( e.g. ship hulls) as well as medical implants. In our laboratory, we setup real-time bacterial adhesion control and observation system using transparent ITO (Indium Tin Oxide) electrode and developed the important concept for controlling bacterial adhesion. These results will be introduced with bacterial behavior movies. we demontrated that the suitable combination of negative and positive current promotes bacterial detachment and inactivation on conductive surfaces.

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  • Jeyong Yoon School of Chemical and Biological Engineering, College of Engineering, Seoul National University

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