원문정보
초록
영어
Glycerol carbonate is a key bifunctionalcompound employed as solvent, additive, monomer, and chemical intermediate. Commercial lipase, Novozym 435 was used to produce the benign monomer glycerol carbonate from renewable starting materials: glycerol and dimethyl carbonate. Tetrahydrofuran was used as the reaction medium to enhance the formation rate of glycerol carbonate and conversion approached quantitative yield. Removal of methanol produced as
by-product duringreaction increased the yield of glycerol carbonate. Other by-products such as glycerol dicarbonate and diglycerol tricarbonate were found. However the total amount of by-products was minute compared with that of glycerol carbonate, which means that lipase-catalyzed reaction is very regioselective for the synthesis of glycerol carbonate.