earticle

영어

In the present study, a randomized, double-blind, placebo-controlled trial to determine the effect of conjugatedlinoleic acid (CLA) supplementation (50:50 ratio of cis-9, trans-11 and trans-10, cis-12 isomers) for 8 weeks on bodycomposition and biochemical parameters in healthy overweight/obese (body mass index, BMI≥23 kg/m2) Korean subjectswas performed. Thirty participants (3 males and 27 females) were randomized to receive placebo (2.4g olive oil/day) or 2.4g/day CLA (mixture containing 36.9% of cis-9, trans-11 and 37.9% of trans-10, cis-12). Eight weeks of CLA supplementationsignificantly decreased body weight by −0.75kg, BMI by −0.27kg/m2, and hip circumference by -1.11 cm. The reduction ofbody weight was ascribed to the reduction of body fat mass (−0.59kg) and lean body mass (−0.18kg), although these changeswere not significant. No significant differences in serum lipid profiles, liver function enzyme activities, and proteinconcentration were observed in either the CLA or placebo groups. These results indicate that short term supplementation (8weeks) with CLA (2.4g/day) may decrease body weight in Korean overweight/obese subjects.