원문정보
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초록
영어
β-Glucans, which were isolated from sangwhang (Phellinus linteus), were subjected to reductive amination and the biological properties of the derivative were investigated. The degree of substitution of the aminated sangwhang β-glucan was calculated by elemental analysis to be 1.13. Bronchoalveolar lavage (BAL) experiments showed that the aminated derivative increased nitric oxide production. In addition, the amination enhanced in vitro cytotoxic activities against HT1080 and SNU-C2A cell lines. Thus, the aminated derivative is shown to enhance immune systems by the incorporation of amino groups into the polymer structure.
목차
Abstract
Introduction
Materials and Methods
Isolation and modification
Biological properties
Statistical analysis
Results and Discussion
Identification of aminated derivative
Effect of amination on nitric oxide production
Effect of amination on tumor cell growth inhibition
References
Introduction
Materials and Methods
Isolation and modification
Biological properties
Statistical analysis
Results and Discussion
Identification of aminated derivative
Effect of amination on nitric oxide production
Effect of amination on tumor cell growth inhibition
References
저자정보
참고문헌
자료제공 : 네이버학술정보