원문정보
초록
영어
The effects of dietary supplementation of the unrefined rice bran oil from 'Suwon 415' pigmented black rice (BRBO) on cholesterol metabolism and cellular antioxidant status were investigated in hypercholesterolemic rats. The significant reduction of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) concentrations was observed in the plasma of rats fed BRBO. BRBO also decreased plasma and hepatic oxidative stress as a result of increased levels of hepatic thiobarbituric acid reactive substances (TBARS) levels associated with the elevations of hepatic superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities together with increased plasma level of tocopherol. This study indicates that dietary BRBO supplement can leads to the improvement of overall cholesterol metabolism and antioxidant status even more effectively than 'Chuchung' white rice (WRBO). Consumption of BRBO may also protect the liver from oxidative damage caused by lipid peroxidation.
목차
Introduction
Materials and Methods
Rices and rice bran oil
Animals and diets
Tissue preparation
Measurment of plasma and hepatic lipids
Measurement of plasma and hepatic lipid peroxides
Measurement of plasma vitamin A and E contents
Determlnation of antioxidant enzyme activities
Statistical analysis
Results and Discussion
Food intakes, body weight, and organ weight
Plasma and hepatic lipids composition
Plasma and hepatic lipid peroxides
Plasma and hepatic antioxidant status
References