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논문검색

Potential Probiotic Properties of Laetoeoeeus laetis NK34 Isolated from Jeotgal

초록

영어

Strain NK34 was characterized for probiotic use. Strain NK34 was named Lactococcus lactis NK34 based on API 50 CHL kit results and 16S rDNA sequencing. L. lactis NK34 was highly resistant to artificial gastric juice (pH 2.5) and artificial bile acid. Based on results from the API ZYM kit, 4 enzymes were produced. L. lactis NK34 was resistant to all antibiotics tested except for 10 ug/mL roxithromycin and 10 ug/mL erythromycin. The cholesterol-lowering effect of L. lactis NK34 was about 46.9%. Concentrations of interleukin (IL)-1a 20xconcentrated supernatant of L. lactis NK34 was about 361 pg/mL. L. lactis NK34 was also found to inhibit the growth of colon cancer cells due to MNNG-induced DNA damage. These results demonstrate the potential of L. lactis NK34 as a health-promoting probiotic.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

저자정보

  • Lee, Na-Kyoung Division of Animal Life Science, Konkuk University
  • Noh, Ji-Eun Division of Animal Life Science, Konkuk University
  • Choi, Gui-Hun Division of Animal Life Science, Konkuk University
  • Park, Eun-Ju Department of Food and Nutrition, Kyungnam University
  • Chang, Hyo-Ihl School of Life Sciences and Biotechnology, Korea University
  • Yun, Cheol-Won School of Life Sciences and Biotechnology, Korea University
  • Kim, Seung-Wook Department of Chemical and Biological Engineering, Korea University
  • Kang, Chang-Won Division of Animal Life Science, Konkuk University
  • Yoon, Yoh-Chang Division of Animal Life Science, Konkuk University
  • Paik, Hyun-Dong Division of Animal Life Science, Konkuk University

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