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논문검색

Effect of Colored Potato Flakes Against Acetaminophen-induced Liver Damage in Rats

원문정보

Ohba, Kiyoshi, Watanabe, Shoko, Han, Kyu-Ho, Hashimoto, Naoto, Noda, Takahiro, Shimada, Ken-Ichiro, Tanaka, Hisashi, Sekikawa, Mitsuo, Fukushima, Michihiro

한국식품과학회 Food Science and Biotechnology Volume 16 Number 3 2007.06 pp.463-469
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

We examined the hepatoprotective effects of colored potato flakes on acetaminophen (AAP)-induced liver damage in rats. F344/DuCrj (8 week-old) rats were fed a cholesterol-free diet with 54.9486 g of -corn starch/100g diet and were orally treated with 25% colored flakes of Kitamurasaki (KM: light purple), Northern Ruby (NR: red), and Shadow Queen (SQ: medium purple) potatoes co-administered with AAP (0.5 g/100 g diet) for 4 weeks. The hepatic thiobarbituric acid-reactive substances (TBARS) values in the KM, NR, and SQ groups were significantly lower (p<0.05) than those in the control groups with and without AAP. Furthermore, the hepatic catalase, Mn-superoxide dismutase (SOD), and Cu/Zn-SOD mRNA levels in the KM, NR, and SQ groups were higher than those in the control groups with and without AAP. The present findings suggest that colored potato flakes are useful as a prophylactic agent against oxidative liver damage.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

저자정보

  • Ohba, Kiyoshi Hokkaido Tokachi Area Regional Food Processing Technology Center
  • Watanabe, Shoko Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine
  • Han, Kyu-Ho Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine
  • Hashimoto, Naoto Department of Upland Agriculture, National Agricultural Research Center for Hokkaido Region
  • Noda, Takahiro Department of Upland Agriculture, National Agricultural Research Center for Hokkaido Region
  • Shimada, Ken-Ichiro Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine
  • Tanaka, Hisashi Somatech Center, House Foods Corporation
  • Sekikawa, Mitsuo Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine
  • Fukushima, Michihiro Department of Agricultural and Life Science, Obihiro University of Agriculture and Veterinary Medicine

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