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논문검색

Hepatopotective Effects of Black Rice on Superoxide Anion Radicals in HepG2 Cells

원문정보

Shim, Sang-In, Chung, Jin-Woong, Lee, Jeong-Min, Hwang, Kwon-Tack, Sone, Jin, Hong, Bum-Shik, Cho, Hong-Yon, Jun, Woo-Jin

한국식품과학회 Food Science and Biotechnology Volume 15 Number 6 2006.12 pp.993-996
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

Cyanidin 3-glucoside (C3G) isolated from black rice was investigated for hepatoprotective effects in HepG2 cells under oxidative stress. When an increase in the production of reactive oxygen species (ROS) was induced by gramoxone, cell viability was drastically decreased by 42%. However, in the presence of C3G, no hepatocytic damage was observed in HepG2 cells treated with gramoxone. C3G was found to manifest a stronger scavenging effect (91%) on superoxide anion radical (O2-) than any of the other natural and synthetic antioxidants. Results suggest that C3G from black rice possesses hepatoprotective effects in vitro, which may be, at least in part, due to O2- scavenging.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 Acknowledgments
 References

키워드

저자정보

  • Shim, Sang-In Division of Plant Resources and Environment, Gyeongsang National University
  • Chung, Jin-Woong Korea Research Institute of Bioscience and Biotechnology
  • Lee, Jeong-Min Department of Food and Nutrition, Nambu University
  • Hwang, Kwon-Tack Department of Food and Nutrition, Nambu University
  • Sone, Jin Jeonnam Innovation Agency
  • Hong, Bum-Shik Department of Food and Biotechnology, Korea University
  • Cho, Hong-Yon Department of Food and Biotechnology, Korea University
  • Jun, Woo-Jin Department of Food and Nutrition, Human Ecology Research Institute, Chonnam National University

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