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Evaluation of the Estrogenic Activity of Isoflavones from the Rhizome of Belamcanda chinensis

원문정보

초록

영어

Four compounds were isolated from the rhizome of Belamcanda chinensis (Iridaceae) by repeated column chromatography and were elucidated as iristectorigenin A, irigenin, tectorigenin and tectoridin by spectral analysis. The estrogenic activity of these isoflavones was tested using Ishikawa cells. Irigenin, tectorigenin and tectoridin were highly estrogenic (£C50 = 0.75, 0.42 and 0.81 ㎍/㎖, respectively), while iristectorigenin A exhibited weak estrogenic activity (£C50≥4 ㎍/㎖).

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References
 Appendix

저자정보

  • Yoo, Hye-Hyun College of Pharmacy, Seoul National University
  • Jin, Yong-Ri Affiliated Hospital, College of Medicine, Yanbian University
  • Jin, Jing-Ling Natural Products Research Institute, Seoul National University
  • Lee, Sang-Hyun College of Pharmacy, Seoul National University

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