원문정보
Evaluation of Biocompatibility of Anodized and Hydrothermally Treated Pure Niobium Metal
초록
영어
This study was performed to investigate the surface properties of electrochemically oxidized pure
niobium by anodic oxide and hydrothermal treatment technique. Niobium specimens of 10 10
in dimension were polished sequentially from #600, #800, #1000 emery paper. The surface pure
niobium specimens were anodized in an electrolytic solution that was dissolved calcium and
phosphate in water. The electrolytic voltage was set in the range of 250 V and the current density
was 10 / . The specimen was hydrothermal treated in high-pressure steam at 300 for 2 hours
using an autoclave. Then, specimens were immersed in the Hanks' solution with pH 7.4 at 37 for
30 days. The surface of specimen was characterized by scanning electron microscope(SEM),
energy dispersive X-ray microanalysis(EDX), potentiostat/galvanostat test, and cytotoxicity test.
The results obtained was summarized as follows; According to the result of measuring corrosion
behavior at 0.9% NaCl, corrosion resistance was improved more specimens treated with anodic oxide than in hydrothermal treated ones. The multi-porous oxide layer on surface treated through
anodic oxidation showed a structure that fine pores overlap one another, and the early precipitation of apatite was observed on the surface of hydrothermal treated samples. According to the result of EDX after 30 days deposition in Hanks solution, Ca/P was 1.69 in hydrothermal treated specimens. In MTT test, specimens treated through anodic oxidation and hydrothermal treated ones showed spectrophotometer similar to that of the control group. Thus no significant difference in cytotoxicity was observed (P>0.05).
목차
Ⅰ. 서론
Ⅱ. 실험재료 및 방법
1. 시편준비
2. 양극산화 및 열수처리
3. 동전위 분극 실험
4. 유사체액 침적 및 표면 분석
5. 세포배양 및 MTT assay
Ⅲ. 실험 결과
1. 부식실험
2. 주사전자현미경 사진
3. 생체활성 평가
Ⅳ. 고찰
Ⅴ. 결론
참고문헌