원문정보
척수강내약물주입펌프 이식술을 시행받은 척수 손상환자에서 주입약제 전환 후 호전된 증례보고 - 척수강내 바클로펜 투여
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The mechanisms of pain in spinal cord injury are very diverse, including peripheral and central neuropathy, muscle spasticity or spasm, secondary musculoskeletal pain due to overuse or atrophy, chronic central sensitization, and visceral pain. More effective treatment is possible if you carefully listen to the patient's medical history and pain pattern. We introduce a 54-year-old male patient who became paraplegic due to spinal cord injury 13 years ago and has been receiving morphine through an intrathecal drug delivery pump since 7 years ago. He mainly complained of severe breakthrough pain accompanied by flexor spasm, which improved significantly after changing administration from morphine to baclofen. Baclofen is FDAapproved for not only spasticity but also for flexor spasm and concomitant pain. Therefore, intrathecal administration of baclofen in patients with spinal cord injury may have a dramatic effect on pain.
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