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Background: The purpose of this study to investigate the effects of an exercise program to improve scapular dyskinesis in breast cancer patients with scapular dyskinesis on body function and quality of life. Methods: Thirty female breast cancer patients with scapular dyskinesis were randomly divided into the scapular dyskinesis improvement exercise program group (SIG; n=15) and the body function improvement exercise program group (BGG; n=15). The study was conducted for a total of 4 weeks, 3 times a week, 50 minutes per session. The evaluation was measured pain was measured using a visual analogue scale (VAS), shoulder range of motion (ROM) was measured, and upper extremity function was measured using the shoulder pain and disability index (SPADI). Quality of life was compared using the functional assessment cancer therapy-breast (FACT-B). Results: After the intervention, there was a significant improvement in VAS (p<.01), shoulder ROM (p<.01), SPADI (p<.01), and FACT-B (p<.01) in both groups after the intervention compared to before. In comparison between groups, SIG showed more significant changes than BGG in shoulder joint ROM in flexion(p<.05), abduction (p<.01), external rotation (p<.01) and SPADI (p<.01), FACT-B (p<.01). Conclusion: This study confirmed the scapular dyskinesis improvement exercise program was an effective intervention for the shoulder range of motion, upper extremity function, and quality of life in breast cancer patients with scapular dyskinesis and the findings suggest that this program can be used as basic data in clinical practice.