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호랑가시나무 초음파 추출물을 이용한 생리활성 연구

원문정보

Effects on Physiological Activities of Ilex cornuta Extracts from Ultrasonification Process

강정욱

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초록

영어

Ilex cornuta traditionally used as a pharmaceutical and food ingredient, was extracted using an ultrasonic-assisted method and evaluated for its cosmetic potential. The total polyphenol content of the Ilex cornuta ultrasonic extract was determined to be 247.21 ± 0.99 mg TAE/100 g. Antioxidant capacity was assessed using DPPH, ABTS, and FRAP assays, revealing that the extract exhibited radical scavenging and reducing activities at concentrations above 500 μg/mL. It reduced α-MSH–induced melanin production by about 20% at 1,000 μg/mL without cytotoxicity. These findings indicate that the ultrasonic extract of Ilex cornuta possesses both antioxidant and skin-whitening properties, suggesting its suitability as a functional cosmetic material.

목차

Abstract
Ⅰ. 서론
Ⅱ. 연구방법
1. 호랑가시나무 추출물 제조
2. 총 폴리페놀 함량 확인
3. DPPH (1,1-diphenyl-2-picrylhydrazyl)를 이용한 전자공여능 저해 활성
4. ABTS (2,2'-azinobis(3-ethylbenzothiazoline-6sulfonic acid)를 이용한 라디칼 소거 활성
5. FRAP (Ferric Reducing Antioxidant Power) 환원력 활성
6. 세포 독성능 평가
7. 멜라닌 생성 억제 활성
8. 통계처리
Ⅲ. 결과 및 논의
1. 호랑가시나무 초음파 추출물의 총 폴리페놀 함량
2. 전자공여능 활성
3. ABTS 라디칼 소거 활성
4. FRAP 활성
5. 멜라닌 유래 세포 독성평가
6. 멜라닌 생성 저해 활성
Ⅳ. 결론 및 제언
참고문헌

저자정보

  • 강정욱 Jung Wook Kang. College of Fusion and Convergence, Seowon university/Assistant professor

참고문헌

자료제공 : 네이버학술정보

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