earticle

영어

This study was conducted to measure DPPH radical scavenging activity, ABTS radical scavenging activity, SOD-like activity, Total polyphenol, Total flavonoid, and content according to the degree of fruit ripening for the development of cosmetic materials from Solanum nigrum L. fruit, and finally, the antibacterial effect against Cutibacterium acnes, Staphylococcus epidermidis, and Malassezia furfur was measured. The DPPH radical scavenging activity was measured at 500 μg/mL of ethanol extracts of unripe and ripe Solanum nigrum L. fruit. The scavenging activity was 80.78 % and 71.12 % respectively, showing that the unripe fruit extract was the highest. It was confirmed that the scavenging activity was lower than that of vitamin C but higher than that of BHT. As a result of measuring ABTS radical scavenging activity, the scavenging activity was confirmed to be 83.26 % and 70.73 % at 500 μg/mL, respectively, indicating that the unripe fruit extract of Kamajung had the highest scavenging activity, and similar scavenging activity to BHT was confirmed. As a result of measuring SOD-like activity, the effects were confirmed to be 60.22 % and 52.53 % at 500 μg/mL, respectively. The total polyphenol contents contained in 1 mg/mL were confirmed to be 255.14 μg/mL and 283.63 μg/mL respectively, and the total flavonoid contents were confirmed to be 121.13 μg/mL and 155.23 μg/mL respectively. The antibacterial effect of ethanol extracts of unripe and ripe fruits of Solanum nigrum L. against C. acnes, S. epidermidis, and M. furfur was measured by the disk diffusion method. The antibacterial effect was confirmed at all concentrations, and the antibacterial effect against M. furfur was particularly high. The results of this study confirmed that Solanum nigrum L. fruits have the potential as a cosmetic material, and the effect of unripe fruits was confirmed to be higher than that of ripe fruits.

한국어

본 연구는 까마중 열매의 화장품 소재 개발을 위해 열매 숙성 정도에 따라 DPPH 라디컬 소거능, ABTS 라디컬 소거능, SOD 유사활성, 총 폴리페놀, 총 플라보 노이드 함량을 측정하였고, 마지막으로 여드름균(Cutibacterium Acnes), 표피포도상구균(Staphylococcus Epidermidis), 말라세지아균(Malassezia Furfur)에 대 한 항균효과를 측정한 결과는 다음과 같다. 까마중 미숙, 완숙 열매 에탄올 추출물 농도 500μg/mL에서 DPPH 라디컬 소거능을 측정한 결과 각각 80.78%, 71.12 %의 소거능이 확인되어 미숙 열매 추출물이 높게 확인되었으며, 비타민 C보다는 낮지만, BHT보다는 높은 소거능이 확인되었다. ABTS 라디컬 소거능을 측정한 결 과 500μg/mL에서 각각 83.26%, 70.73%의 소거능이 확인되어 까마중 미숙 열매 추출물이 높게 확인되었으며, BHT와 유사한 소거능이 확인되었다. SOD 유사활 성을 측정한 결과 500μg/mL에서 각각 60.22%, 52.53% 효과가 확인되었다. 1mg/mL에 포함되어있는 총 폴리페놀 함량은 각각 255.14μg/mL, 283.63μg/mL 함 량이 확인되었으며, 총 플라보노이드는 각각 121.13μg/mL, 155.23μg/mL 함량이 확인되었다. 까마중 미숙, 완숙 열매 에탄올 추출물의 여드름균, 표피포도상구 균, 말라세지아균에 대한 항균 효과를 디스크 확산법으로 측정한 결과 모든 농도에서 항균효과가 확인되었으며, 특히 말라세지아균에 대한 항균효과가 높게 확인 되었다. 이상의 연구 결과 까마중 열매는 화장품 소재 가능성이 확인되었으며, 미숙 열매가 완숙 열매 보다 효과가 높게 확인되었다.