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Purpose: The purpose of this study was to examine the extent of work-related contact after working hours and work-life balance among shift work nurses and the impact of work-related contact after working hours on work-life balance. Methods: A descriptive research design was used with a convenience sample of 165 nurses. Data were collected from August 1 to August 31, 2024 using self-reported questionnaires. Data were analyzed with a t-test, ANOVA, Pearson’s correlation, and multiple linear regression analyses using SPSS/WIN 30 software. Results: We found that work-life balance was significantly and negatively related to age (β=-.42, p<.001) and the degree of work-related contact after working hours (β=-.19, p=.016), with an explanatory power of 24.6% (F=4.54, p<.001). Conclusion: This study highlights the importance of reducing unnecessary work-related contact after working hours and improving work-life balance, which is expected to enhance not only job satisfaction but also the quality of life of shift work nurses.