원문정보
초록
영어
Background: Boron neutron capture therapy (BNCT) is a potential radiation therapy for treating refractory cancers. Measuring the neutron energy spectrum is important to evaluate the biological effect of BNCT. We have developed a novel low-energy neutron spectrometer with a 3He position-sensitive proportional counter. The effectiveness of this spectrometer remained unvalidated due to the inadequate response function. Materials and Methods: The response function of this spectrometer was evaluated by Monte Carlo simulation to perform the validation experiment of this spectrometer. The 3He(n,p)3H reaction rate for each monochromatic neutron (energy range, 0.5 eV–10 keV) was calculated. Numerical experiments were conducted to investigate the performance of this spectrometer. Several estimated values of the energy spectrum were obtained and compared with a calculated energy spectrum at the exit of the epithermal column by the Monte Carlo simulation by preparing several candidates for signals. The Bayesian estimation algorithm was utilized for the estimation. Results and Discussion: The results indicate that the spectrometer and the evaluated response functions can be utilized to measure the energy spectrum of neutrons in the low-energy range. However, the energy spectrum could not be well represented >4 keV due to the poor response function, including uncertainties in response function calculation as well as the poor energy resolution of this detector in the high-energy region. Conclusion: The response function of the low-energy neutron spectrometer for the epithermal energy region can be assessed by the Monte Carlo simulation. The numerical experiments reveal that the effectiveness of this spectrometer can be shown in the range of 0.5 eV.
목차
Introduction
Materials and Methods
Results and Discussion
Conclusion
Conflict of Interest
Ethical Statement
Author Contribution
References
