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원저논문

생체용 타이타늄 합금의 산화거동 및 세포독성에 관한 연구

원문정보

A Study on Oxidation Behavior and Cytotoxicity Test of Ti-10Ta-10Nb Alloy

조홍규, 이도재, 이광민, 이경구

피인용수 : 0(자료제공 : 네이버학술정보)

초록

영어

A new Ti-10Ta-10Nb alloy has designed and examined some possibility of forming more passiveoxide film by oxidation treatment which is closely related to corrosion resistance andbiocompatibility. Ti-6Al-4V and Ti-10Ta-10Nb alloys were prepared by consumable vacuum arcmelting and homogenized at 1050for 24hours. Alloy specimens were oxidized at thetemperature range of 400 to 750for 30minutes, and the oxide films on Ti alloys were analysedby optical microscope, SEM, XPS and TGA. Cytotoxicity test was performed in MTT assay treatedL929 fibroblast cell culture by indirect method.It is found out that the oxide film on Ti-10Ta-10Nb alloy is denser and thinner compared to Ti-6Al-4V alloy. The weight gain during the oxidation was increased rapidly at the temperature above650for Ti-6Al-4V alloy and above 700for Ti-10Ta-10Nb alloy respectively. It was analysedthat the passive film of the Ti alloys consisted of TiO2 through X-ray photoelectron spectroscopy(XPS) analysis. It is found out by cytotoxicity test that moderate oxidation treatment lowers celltoxicity, and Ti-10Ta-10Nb alloy showed better result compared to Ti-6Al-4V alloy.

목차

Abstract
 Ⅰ. 서론
 Ⅱ. 연구방법
  1. 합금제조
  2. TGA실험
  3. 산화 실험
  4. ESCA 분석
  5. 용출시험
  6. 세포독성시험(cytotoxicity test)
 Ⅲ. 연구결과및고찰
 Ⅳ. 결론
 참고문헌

저자정보

  • 조홍규 Hong-Kyu Cho. 광주보건대학 치기공과
  • 이도재 Doh-Jae Lee. 전남대학교 공과대학 신소재공학부
  • 이광민 Kwang-Min Lee. 전남대학교 공과대학 신소재공학부
  • 이경구 Kyung-Ku Lee. 전남대학교 공과대학 신소재공학부

참고문헌

자료제공 : 네이버학술정보

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