earticle

영어

Enrofloxacin is a fluoroquinolone-based synthetic antimicrobial agent that exhibits potent bactericidal effects against gram-positive and gram-negative bacteria that infect aquatic animals. Thus, it is effective in treating bacterial infections in fish. However, antibiotic (enrofloxacin) residues in fish food or fish feed can threaten to human health in association with the development of antibiotic-resistant bacteria. In this case, the dead fish that may have included enrofloxacin residues was turned into fish feed and then sold to fish farmers. A total of 61 fish feed was asked to be examined for the presence of enrofloxacin. Therefore, this present study aimed to analyze enrofloxacin residues in fish feed by liquid chromatography quadrupole time-of-flight mass spectrometry(LC-QTOF/MS). For sample pretreatment, the QuEChERS(Quick, Easy, Cheap, Effective, Rugged, and Safe) method was applied to extract enrofloxacin from the sample and minimize matrix effects. As a result, enrofloxacin was detected in all the fish feed samples.