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Purpose: This study aimed to explore the use of web-based virtual simulations to improve the learning flow, problem-solving ability, and academic self-efficacy of paramedicine students. Methods: This study used a pre–post comparison design with 40 pamedicine students at one university. the participants were third grade students and participated in web based virtual simulation(vSimⓇ). The difference between the pre-post was analyzed using a Paired Sample t-test with SPSS 26.0. Results: After web based virtual simulation using vSimⓇ program than before, significantly higher learning flow(t=12.74, p<.001), problem-solving process(t=5.78, p<.001), academic self-efficacy(t=2.77, p<.001), Paramedic-Care Skills Confidence(t=6.30, p<.001). Conclusion: The results indicated the positive effects of web-based virtual simulation(vSimⓇ) learning method and suggests implications for learners and instructors.