earticle

영어

The emerging infectious diseases, particularly viral infections in animals (zoonotic host species such as domestic, semi-domestic livestock, poultry, pets, bats and rodents), are major concern around the world. In Bangladesh, the most important animal viral diseases are Nipah virus (fruit bats), lumpy skin diseases virus (cattle and water buffalo), west nile virus (mosquito-borne), swine fever virus (pigs and wild boar), and many others. However, lumpy skin disease is one of viral diseases caused by lumpy skin disease virus (LSDV). LSDV is primarily spread by arthropod vectors such as flies, mosquitos, ticks and direct or indirect contact between infected and susceptible animals. Based on an economic loss analysis, the average loss per case due to LSDV was 9384.41 BDT (110.40 US $). The major losses have been accounted for it by treatment costs, extra management costs, lower animal selling prices, labor costs, and income loss resulting in lower milk yield. On September 15, 2019, OIE (World Organization for Animal Health) reported that the disease first appeared in the Southeast region of Bangladesh (Chattogram district), then progressively spread throughout the entire country. So far, six LSD outbreaks in Bangladesh have been documented with the clinical signs and collect samples for diagnostic confirmation. The genomic profile of LSDVs circulating in Bangladesh are unknown. The virus (LSDV) has a double-stranded DNA genome, which is about 151,000 bp in size, encoding approximately 156 proteins. The previous research finding that Bangladesh isolates differ from common LSDV field isolates encountered in Africa, the Middle East, and Europe, as well as newly emerged LSDV variants in Russia and China, based on a phylogenetic analysis and detailed inspection of multiple sequence alignments. Finally, for biosecurity and management practices, transmission dynamics, continuous monitoring, and genomic characterization of circulating strains of LSDV should be prioritized.