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Nanocellulose assisted hydrogel platforms for improved wound healing and biosensing applications

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The development of multifunctional wearable electronic devices has received considerable attention because of their attractive applications. However, integrating multifunctional abilities into one component remains a challenge. To address this, we have developed a tannic acid-functionalized spherical nanocellulose/polyvinyl alcohol composite hydrogel using borax as a crosslinking agent for strain-sensing applications. The hydrogel demonstrates improved mechanical and recovery strengths and maintains its mechanical strength under freezing conditions. The hydrogels show ultra-stretching, adhesive, self-healing, and conductive properties, making them ideal candidates for developing strain-based wearable devices. The hydrogel exhibits good sensitivity with a 4.75 gauge factor at 360% strain. The cytotoxicity of the developed hydrogels is monitored in human dermal fibroblast cells by WST-8 assay in vitro. The antibacterial potential of the hydrogels is evaluated using Escherichia coli. The developed hydrogels demonstrate enhanced antibacterial ability compared with the control. Thus, multifunctional hydrogels with desirable properties are a promising platform for designing strain-based sensor devices.

저자정보

  • Dinesh K. Patel Department of Biosystems Engineering, Institute of Forest Science, Kangwon National University
  • Ki-Taek Lim Department of Biosystems Engineering, Institute of Forest Science, Kangwon National University

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