원문정보
초록
영어
Poly(hydroxyethyl acrylate-co-phenyl vinyl sulfide)(poly(HEA-co-PVS) was polymerized by free radical reaction. The polymerization of poly(HEA-co-PVS) was confirmed by UV spectrum and 1H NMR analysis. The amphiphilic property of poly(HEA-co-PVS) was confirmed by interfacial tension analysis. Poly(HEA-co-PVS) oxidized by H2O2 (oxidation-poly(HEA-co-PVS)) was lost amphipathicity. The lower critical solution temperature was observed by the optical density change of the poly(HEA-co-PVS) solution according to the temperature change, and the LCST of oxidation-poly(HEA-co-PVS) was increased. Poly(HEA-co-PVS) micelle was prepared by thin film method. The prepared poly(HEA-co-PVS) micelle was observed to be spherical through transmission electron microscope (TEM). The release degree of poly(HEA-co-PVS) micelle loaded nile red (fluorescent dye) was examined by temperature and oxidation stimulation. The release degree of poly(HEA-co-PVS) micelle was more dependent on temperature (above LCST) and oxidation conditions.