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Purpose: This quasi-experimental study used a non-equivalent control group pretest-posttest design with clinical nurses to develop a compassion improvement program and verify its effects on compassion competence and empathic communication. Methods: The Triandis Interpersonal Behavior model (Triandis, 1980) was used as a theoretical framework, and a compassion improvement program was developed based on the ADDIE model. The experimental treatment in the program was conducted for 120 minutes per session, once a week, for a total of six sessions. The data collection and research period ranged from September 7 to November 16. It involved a pre-survey of measured variables, six sessions of experimental treatment, a post-survey, and a follow-up survey in sequence. The collected data were analyzed using the statistical program SPSS/WIN 25.0 and then based on a t-test and repeated measures ANOVA to verify the effectiveness of the program. Results: Clinical nurses participating in the compassion improvement program showed improved compassion competence (F=8.00, p=.001) due to the cultivation of insight, sensitivity, and communication skills. In addition, the improvement in attentive listening (F=3.32, p=.024) indicated that the program was partially effective in empathic communication.