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Purpose: The purpose of this study was to determine the level of depression, anxiety, and stress among health college students and to identify factors affecting sleep quality to provide a basis for improving sleep quality among health college students. Methods: Data was collected using a structured questionnaire from 181 college students at a university in City D from October 1 to October 31, 2023. Results: Sleep quality was significantly and positively correlated with depression (r=.703, p<.001), anxiety (r=.680, p<.001), and stress (r=.708, p<.001), and its predictors were caffeine consumption (β =-.174, p=.044), Satisfaction with college life (β=-.137, p=.009), depression (β=.251, p=.013). Stress (β=.277, p=.007), with an explanatory power of 56%. Conclusion: To improve the sleep quality of college students, we should encourage them to reduce their caffeine intake, run various programs to improve their satisfaction with college life, and expand mental health counseling programs on campus to monitor their mental health status regularly so that they can actively manage depression and stress.