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Purpose: This study aimed to investigate the trends in domestic research related to health literacy in children and adolescents. Methods: Six journal articles and four dissertations or theses related to health literacy in children and adolescents were analyzed according to the following criteria: study aim, research design, study population and sample size, sampling method, health literacy variables, and characteristics of health literacy measurement instruments. Result: The majority of studies focused on general children and adolescents. Correlational studies were most prevalent, while no experimental study was identified at all. The variable most frequently explored in relation to health literacy was health promoting behaviors. Functional health literacy instruments, assessing numeracy and reading comprehension, were most commonly used to evaluate child and adolescent health literacy. Conclusion: Considering the emphasis on health literacy improvement in order to achieve health equity across the entire life cycle, there is a need for both quantitative and qualitative growth in domestic health literacy studies for children and adolescents. School-based interventions are essential for enhancing health literacy. Furthermore, it is also necessary to develop an instrument to measure health literacy of children and adolescents that can be utilized and monitored at the national level.