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Objectives: This study is to implement a mindfulness meditation program and evaluate its effects in helping recovering alcoholics cope with addiction-related problems and stress with goals of healthy lifestyle changes to prevent relapse and maintain recovery. Methods: A concurrent embedded mixed-method design was used to evaluate the effects of the mindfulness meditation program. Nonequivalent control group pretest-posttest design was applied to verify the quantitative effects of the program. Quantitative data with 44 participants (experimental group: 23, control group: 21) were analyzed using a linear mixed-model. Regarding qualitative research, the contents of the individual interviews with 6 participants were analyzed through the content analysis method. Results: There were significant differences between the experimental and the control groups in terms of changes in perceived stress (F=14.01, p<.001), mindfulness (F=5.68, p=.019), alcohol abstinence self-efficacy (F=32.74, p<.001), and perceived health status (F=5.31, p=.024) at the pretest, posttest, and follow-up test. However, there were no significant changes regarding health-related quality of life (F=.40, p=.530) between the two groups. In addition, a total of three themes and six sub-themes were derived through content analysis of the individual interviews. The themes included “stopping and observing”, “choosing healthy coping”, and “starting newly”. The sub-themes were related to “distancing”, “finding myself”, “caring about my body and mind”, “letting go of for change”, “going with others” and “expecting changes in myself”. Conclusions: The mindfulness meditation program can be used as an effective aftercare program to help prevent relapse and maintain the recovery process for alcoholics. In addition, this study’s results can provide useful data for nursing education and research related to alcoholism.